Little Debbie's - Oatmeal Creme Pie (Big) calories, carbs & nutrition ... Little Debbie's - Oatmeal Creme Pie (Big) Serving Size : 1 Cookie. 330 Cal. 59 % 52g Carbs. 38 % 15g Fat. 2 % 2g Protein. ... Daily Goals. How does this food fit into your daily goals? Calorie Goal 1,670 cal. 330 / 2,000 cal left. Fitness Goals : Heart Healthy. Fat 52g. 15 / 67g left. Sodium 1,990g. 310 / 2,300g left. Cholesterol 300g--/ 300g ...